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The three major clinical patterns are streaks and swirls following the Blaschko lines figure 1 a segmental or checkerboard. Il sagit dune affection rare caractrise par une hypopigmentation suivant les lignes de Blaschko et dont la gravit. Pdf Neurological Pictures Hypomelanosis Of Ito Distribution and a phylloid leaf-like. Hypopigmentation de ito . Incontinentia pigmenti achromians. 4122021 Hypohidrosis of hypopigmented skin can be detected in hypomelanosis of Ito by application of iodine and starch in the skin followed by a subcutaneous injection of pilocarpine hydrochloride. Hypomelanosis of Ito also called incontinentia pigmenti achromians is a very rare birth defect that causes streaked whirled or mottled patches of light-colored hypopigmented skin 1. Diminuer la coloration de l piderme. 12152014 Lhypopigmentation correspond. Neurologic impairment can be quite severe with. Lassociation possible avec dautres anomalies en particulier neurologiques squelettiques